• Heisman Trophy (2017)
• 2x Heisman Trophy Finalist (2016, 2017)
• Maxwell Award (2017)
• Walter Camp Award (2017)
• Davey O’Brien Award (2017)
• Associated Press Player of the Year (2017)
• 2× Sporting News Player of the Year (2015, 2017)
• 2× Burlsworth Trophy (2015, 2016)
• 2× Big 12 Offensive Player of the Year (2015, 2017)
• Big 12 Offensive Freshman of the Year (2013)
• 2× First-team All-American (2015, 2017)
• 3× First-team All-Big 12 (2015–2017)
• NFL Rookie QB QBR Leader (2018)
• NFL Rookie QB Pass Completions Leader (2018)
• NFL Rookie QB Pass Attempts Leader (2018)
• NFL Rookie QB Pass Completion Percentage Leader (2018)
• NFL Rookie QB Pass Attempts per Game Leader (2018)
• NFL Rookie QB Pass Yards Leader (2018)
• NFL Rookie QB Pass Yards per Pass Attempt Leader (2018)
• NFL Rookie QB Pass Yards per Game Leader (2018)
• NFL Rookie QB Pass Touchdowns Leader (2018)
• 7× Pepsi NFL Rookie of the Week (2018 Weeks 3, 7, 9, 12, 14, 16, 17)
• AFC Offensive Player of the Week (2018 Week 16)
• PFT Rookie of the Year (2018)
• PFWA Rookie of the Year (2018)
• PFF Offensive Rookie of the Year (2018)
• PFWA All-Rookie Team (2018)

NCAA records/accomplishments

• First walk-on transfer student to win Heisman Trophy
• NCAA passer rating leader (2017) [203.8]
• 2x NCAA passing efficiency rating leader (2016, 2017) [196.4, 198.9]
• 2x NCAA yards per attempt leader (2016, 2017) [11.1, 11.5]
• 2x NCAA adjusted passing yards per attempt leader (2016, 2017) [12.3, 12.9]
• 2x NCAA pass completion percentage leader (2016, 2017) [70.9, 70.5]
• NCAA total yards per play leader (2017) [9.9]
• NCAA TDs responsible for leader (2017) [49]

Oklahoma Sooners football records

• Most career total touchdowns — 137 (119 passing, 18 rushing)
• Highest career passing completion percentage — 69.8 (tied)
• Most passing yards in a game — 598
• Most passing touchdowns in a game — 7

NFL records

• Most passing touchdowns by a rookie quarterback — 27.

Career

• Most uninterrupted consecutive games with at least 2 passing touchdowns — 5

Season

• Most Passing Yards per Game – 266.1

Rookie season

• Most Passing Touchdowns — 27
• Highest QBR — 55.7
• Highest Passer Rating — 93.7
• Highest Completed Pass Percentage — 63.8
• Highest Net Yards per Pass Attempt — 6.95
• Highest Adjusted Net Yards per Pass Attempt — 6.77
• Lowest Percentage of Sacks per Pass Attempt — 4.9
• Most Passing Completions — 310
• Most Passing Yards — 3,725
• Most Passing Yards per Game – 266.1
• Most 4th quarter Comebacks — 3
• Most Game Winning Drives — 4
• Most Passing Yards in a Game — 397
• Most Touchdown Passes in a game — 4
• Most Passing Completions in a game — 29 (Done twice, tied with Tim Couch)
• High Passing Completion Percentage in a game — 85.0 (17/20, Week 10)